abstract：:BACKGROUND Rheumatoid arthritis (RA) is an inflammatory disorder that is present in approximately 1% of the world's population. This study was aimed to investigate the effect of retinoic acid-platinum (II) complex [RT-Pt(II)] on rheumatoid arthritis (RA) and to explore the mechanism involved. MATERIAL AND METHODS MH7A...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Cui Z,Lin Y,Liu Y,Cao L,Cui L

更新日期：2020-08-03 00:00:00

abstract：:BACKGROUND This study investigated the effect of occupational stress and circadian clock gene polymorphism on sleep disorder of oil workers in Xinjiang, China. MATERIAL AND METHODS We enrolled 2300 Xinjiang oil workers who had been working for at least 1 year. The Chinese revised version of the Occupational Stress Que...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Ning L,Shi L,Tao N,Li R,Jiang T,Liu J

更新日期：2020-08-01 00:00:00

abstract：:BACKGROUND The incidence of osteoclast-like giant cell tumor of the pancreas (OGTP) is very low, and relatively little OGTP clinical data is available. The present study, therefore, sought to conduct a more comprehensive analysis of the clinical characteristics and prognosis of OGTP. MATERIAL AND METHODS A large popul...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Xu M,Chen W,Wang D,Nie M

更新日期：2020-07-27 00:00:00

abstract：:BACKGROUND Fibrinogen-like protein 2 (FGL2) is a member of the fibrinogen-like protein family and possesses important regulatory functions in both innate and adaptive immune responses. FGL2 is overexpressed in glioma, and its expression level is negatively associated with the prognosis of glioma patients. However, the...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Feng Y,Guo C,Wang H,Zhao L,Wang W,Wang T,Feng Y,Yuan K,Huang G

更新日期：2020-07-27 00:00:00

abstract：:BACKGROUND Ethnic background may affect the prevalence of nasal bone absence and the length of the nasal bone. This study aimed to elucidate the significance of absent or hypoplastic fetal nasal bone in the Chinese Han population and to formulate an optimal management plan for patients age 35 or older in cases of isol...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Chen Y,Lv M,Dong T,Chen Q,Qian Y,Zhao B,Luo Q

更新日期：2020-07-26 00:00:00

abstract：:BACKGROUND We aimed to investigate the functions of long non-coding RNA (lncRNA) non-coding RNA activated by DNA damage (NORAD) in glioma and identify the potential mechanisms. MATERIAL AND METHODS The expression of NORAD and AKR1B1 in human glioma cell lines were examined using reverse transcription-quantitative poly...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Luo L,Chen C,He H,Cai M,Ling C

更新日期：2020-07-21 00:00:00

abstract：:BACKGROUND The management of chronic unilateral hematuria (CUH) caused by benign lesions is a therapeutic challenge to many urologists. The aims of this study were to evaluate the efficacy and safety of povidone iodine sclerotherapy for CUH. MATERIAL AND METHODS We identified 20 patients who underwent povidone iodine ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Hu Z,Zhang Y,Liu J,Wu H,Wang F,Jin X

更新日期：2020-07-21 00:00:00

abstract：:BACKGROUND The C677T polymorphism of the 5,10-methylenetetrahydrofolate reductase (MTHFR) gene polymorphism has been associated with hypertension and coronary heart disease, but its relationship with carotid artery remains unknown. This study aimed to investigate the association between the C677T polymorphism of the M...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Li A,Huang W,Yang Q,Peng L,Liu Q

更新日期：2020-07-17 00:00:00

abstract：:In December 2019, an outbreak of coronavirus infection emerged in Wuhan, Hubei Province of China, which is now named Coronavirus Disease 2019 (COVID-19). The outbreak spread rapidly within mainland China and globally. This paper reviews the different imaging modalities used in the diagnosis and treatment process of CO...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Jiang ZZ,He C,Wang DQ,Shen HL,Sun JL,Gan WN,Lu JY,Liu XT

更新日期：2020-07-12 00:00:00

abstract：:BACKGROUND The long non-coding RNA (lncRNA) metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) is expressed highly in various types of tumors. Moreover, the tumor-initiating role of MALAT1 has been probed in the context of breast cancer. This study was set to investigate the regulatory role of MALAT1 on t...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Yu J,Jin T,Zhang T

更新日期：2020-07-05 00:00:00

abstract：:BACKGROUND Thyroid nodules are extremely common and typically diagnosed with ultrasound whether benign or malignant. Imaging diagnosis assisted by Artificial Intelligence has attracted much attention in recent years. The aim of our study was to build an ensemble deep learning classification model to accurately differe...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Wei X,Gao M,Yu R,Liu Z,Gu Q,Liu X,Zheng Z,Zheng X,Zhu J,Zhang S

更新日期：2020-06-18 00:00:00

abstract：:BACKGROUND Dilated cardiomyopathy (DCM), which is characterized by enlarged ventricular dimensions and systolic dysfunction, is the most common type of cardiomyopathy. Mutations in the LMNA gene are reported in approximately 10% of familial DCM cases. However, the mechanism of LMNA mutations in human DCM remains uncle...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhou H,Tan L,Lu T,Xu K,Li C,Liu Z,Peng H,Shi R,Zhang G

更新日期：2020-06-14 00:00:00

abstract：:BACKGROUND This study aimed to compare the predictive role of two-dimensional transthoracic echocardiography (2D-TTE) and three-dimensional transthoracic echocardiography (3D-TTE) on in-hospital all-cause mortality in patients with heart failure and reduced ejection fraction (HFrEF) due to ischemic heart disease (IHD)...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Lu A,Fan H,Xu J,Li J,Zhao H

更新日期：2020-06-07 00:00:00

abstract：:BACKGROUND The aim of this study was to investigate the ability of coronary computed tomographic angiography (CCTA) characteristics of high-risk plaque (HRP) in moderate stenosis to improve differentiation of myocardial ischemia detected by stress CT perfusion (CTP) imaging. MATERIAL AND METHODS Sixty-two patients wit...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Qi L,Shi K,Li C,Ju Z,Mao D,Zhang L,Qu X,Hua Y,Li M

更新日期：2020-06-04 00:00:00

abstract：:BACKGROUND The present research aimed to explore the risk factors for adverse cardiovascular events in elderly patients with acute myocardial infarction (AMI) combined with NAFLD. MATERIAL AND METHODS We included 325 AMI patients hospitalized in the Department of Cardiology. AMI patients underwent emergency thrombolys...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Xia W,Yang N,Li Y

更新日期：2020-06-01 00:00:00

abstract：:BACKGROUND The aim of this study was to compare the clinical safety and effectiveness of transurethral bipolar plasmakinetic enucleation of the prostate (PKEP) vs. transurethral bipolar plasmakinetic resection of the prostate (PKRP) in the treatment of benign prostate hyperplasia (BPH) more than 80 ml. MATERIAL AND ME...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Jiang Y,Bai X,Zhang X,Wang M,Tian J,Mu L,Zhang N,Li M,Du Y

更新日期：2020-04-27 00:00:00

abstract：:BACKGROUND The current research work aimed to explore the protective role of myricetin against cataractogenesis in humans, in terms of its anti-apoptotic potential. MATERIAL AND METHODS Human eye lens epithelial cells were exposed to oxidative stress by treating with hydrogen peroxide (H₂O₂). The levels of superoxide ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Yang Y,Xu X,Liu Q,Huang H,Huang X,Lv H

更新日期：2020-04-26 00:00:00

abstract：:BACKGROUND Hypertension and diabetes mellitus (DM) are both the risk factors for cancer. This study aimed to explore the prognostic value of fasting blood glucose (FBG) and hypertension in type 2 DM (T2DM) patients with advanced non-small cell lung cancer (NSCLC) who had received chemotherapy treatment. MATERIAL AND M...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zeng X,Zeng D,Cheng J,Xu C,Sun C,Long H,Zhu B

更新日期：2020-04-19 00:00:00

abstract：:BACKGROUND Pulmonary arterial hypertension (PAH) is characterized by a progressive increase in pulmonary circulatory resistance. Pulmonary vascular endothelial dysfunction is one of the main causes of primary PAH. Endothelial progenitor cells (EPCs) can proliferate and differentiate into vascular endothelial cells and...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Wang Y,Zhong B,Wu Q,Tong J,Zhu T,Zhang M

更新日期：2020-04-18 00:00:00

abstract：:BACKGROUND Hesperidin (HPD) is a bioflavonoid found in citrus fruits. This study aimed to investigate the effects of HPD on cerebral morphology and cognitive behavior in sevoflurane anesthetized neonatal rats and the molecular mechanisms involved. MATERIAL AND METHODS Sixty neonatal Sprague-Dawley rats were divided in...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Huang H,Hu C,Xu L,Zhu X,Zhao L,Min J

更新日期：2020-04-16 00:00:00

abstract：:BACKGROUND The aim of our study was to investigate the risk factors for falls in the rheumatoid arthritis (RA) patient population in Poland. This would be a major step towards the development of new fall prevention programs. MATERIAL AND METHODS There were 450 RA patients who met the criteria of the American College o...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Mikos M,Kucharska E,Lulek AM,Kłosiński M,Batko B

更新日期：2020-04-15 00:00:00

abstract：:BACKGROUND Levetiracetam (LEV) is an antiepileptic drug that promotes recovery of neurological function by alleviating inflammatory reactions. However, it is not known whether it can improve secondary brain injury after intracerebral hemorrhage (ICH). The aim of this study was to determine whether LEV can reduce early...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Xiong J,Zhou H,Lu D,Wang Z,Liu H,Sun Y,Xu J,Feng Y,Xing A

更新日期：2020-04-14 00:00:00

abstract：:We have retracted this publication because we were informed that an image used by the authors was copied from the following article: J Korean Neurosurg Soc. 2011 Nov; 50(5): 441-445. Minimally Invasive Multi-Level Posterior Lumbar Interbody Fusion Using a Percutaneously Inserted Spinal Fixation System: Technical Tips,...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Liu X,Li G,Wang J,Zhang H

更新日期：2020-04-09 00:00:00

abstract：:BACKGROUND Aging is characterized by progressive deterioration in metabolic and physiological process. The present research assessed the antagonistic effects and mechanisms of Ginsenoside Rg1 (Rg1) on aging of HSCs/HPCs. MATERIAL AND METHODS Fifty male Sprague-Dawley (SD) rats were treated and divided into the followi...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhou Y,Wang YP,He YH,Ding JC

更新日期：2020-04-07 00:00:00

abstract：:BACKGROUND Type 2 diabetes mellitus (T2DM) and its comorbidities, including obesity, hypertension, and hyperlipidemia, are commonly associated with non-alcoholic fatty liver disease (NAFLD). Ganoderma lucidum polysaccharide (GDLP) is one of the central bioactive components in Ganoderma lucidum with anti-inflammatory, ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Li HN,Zhao LL,Zhou DY,Chen DQ

更新日期：2020-04-04 00:00:00

abstract：:BACKGROUND In most cases, biliary tract intraductal papillary mucinous neoplasm (BT-IPMN) is depicted by pathological features rather than on imaging modalities, but fine-needle aspiration cytology cannot provide complete information on tumor(s). Computed tomography (CT) has the advantage of high spatial resolution an...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Li J,Yu Y,Zhu L,Li Y,He Q

更新日期：2020-04-01 00:00:00

abstract：:BACKGROUND Wilms tumor, or nephroblastoma, is a malignant pediatric embryonal renal tumor that has a poor prognosis. This study aimed to use bioinformatics data, RNA-sequencing, connectivity mapping, molecular docking, and ligand-protein binding to identify potential targets for drug therapy in Wilms tumor. MATERIAL A...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Luo JY,Yan SB,Chen G,Chen P,Liang SW,Xu QQ,Gu JH,Huang ZG,Qin LT,Lu HP,Mo WJ,Luo YG,Chen JB

更新日期：2020-03-26 00:00:00

abstract：:BACKGROUND Esophageal squamous cell carcinoma (ESCC), a major histological subtype of esophageal cancer, is a common cause of tumor-related deaths in the world. Due to the lack of understanding of the pathogenesis of ESCC, its clinical treatment is still a big challenge. In the present study, we aimed to identify an E...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Wang X,Gu M,Ju Y,Zhou J

更新日期：2020-03-24 00:00:00

abstract：:BACKGROUND Chronic obstructive pulmonary disease (COPD), a general airway disease, is featured by progressive and chronic immunoreaction in the lung. Increasing evidences have showed that cigarette smoking is the main reason in the COPD progression, and human pulmonary microvascular endothelial cell (HPMEC) apoptosis ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Bi H,Wang G,Li Z,Zhou L,Zhang M,Ye J,Wang Z

更新日期：2020-03-23 00:00:00

abstract：:BACKGROUND From the end of December 2019, coronavirus disease 2019 (COVID-19) began to spread in central China. Social capital is a measure of social trust, belonging, and participation. This study aimed to investigate the effects of social capital on sleep quality and the mechanisms involved in people who self-isolat...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Xiao H,Zhang Y,Kong D,Li S,Yang N

更新日期：2020-03-20 00:00:00

abstract：:BACKGROUND Recent studies have suggested that hepatocyte senescence could contribute to hepatic steatosis and its progression in nonalcoholic fatty liver disease (NAFLD). However, the underlying mechanism causing hepatocyte senescence in this pathological condition is still unclear. A thorough understanding of the mec...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhang J,Li Y,Wang B,Luo Y,Shi J,Zhao B

更新日期：2020-03-19 00:00:00

abstract：:BACKGROUND Following total knee arthroplasty (TKA), postoperative patient rehabilitation is important to achieve the optimal level of knee function and mobility. Clinical research in this field is growing, and bibliometric analysis of publication may provide direction for research clinicians and raise awareness of res...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Wang SQ,Gao YQ,Zhang C,Xie YJ,Wang JX,Xu FY

更新日期：2020-03-17 00:00:00

abstract：:BACKGROUND Neonatal acute respiratory distress syndrome (ARDS) is a common clinical syndrome caused by lung immaturity and the abnormal synthesis of pulmonary surfactant in preterm newborns, and it has high morbidity and mortality rates. The present study investigated the roles of interleukin-37 (IL-37) in the pathoge...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Li B,Ji X,Tian F,Gong J,Zhang J,Liu T

更新日期：2020-03-10 00:00:00

abstract：:BACKGROUND This study was conducted to analyze the activity of masticatory muscles depending on the presence of temporomandibular joint disorders (TMD) when foods of various hardness are masticated. MATERIAL AND METHODS We enrolled 20 subjects (13 men and 7 women) who met our selection criteria, and they were divided ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Cho GH,Lee Y

更新日期：2020-03-10 00:00:00

abstract：:BACKGROUND Gastric cancer (GC) is a life-threating malignancy worldwide. Accumulating studies suggest propofol has anti-tumor functions in addition to the anesthetic effect. This study aimed to figure out the effects of propofol treatment in GC development. MATERIAL AND METHODS Human GC SGC-7901 and NCI-N87 cells were...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Liu F,Qiu F,Fu M,Chen H,Wang H

更新日期：2020-03-02 00:00:00

abstract：:BACKGROUND Alzheimer disease (AD) is a significant health issue for the elderly, and there are at present no clinically effective anti-AD agents. Prevention of Aß-induced neurotoxicity is proposed as a possible modality for treatment of AD. miR-33 has been proven to promote Aß secretion and impair Aß clearance in neur...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Wang X,Li X,Huang B,Yang L,Chen K,Zhao D,Luo X,Wang Y

更新日期：2020-03-02 00:00:00

abstract：:BACKGROUND Few studies have examined functional brain changes specifically associated with chemotherapy (CTx) in patients with lung cancer. This prospective longitudinal research aimed to explore the change in intrinsic brain activity by investigating patients with lung cancer after CTx. MATERIAL AND METHODS Sixteen p...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： You J,Hu L,Zhang Y,Chen F,Yin X,Jin M,Chen YC

更新日期：2020-02-18 00:00:00

abstract：:BACKGROUND Inositol is an essential nutrient for cell growth, survival and embryonic development. Myo-inositol is the predominant form in natural. To investigate the correlation between inositol metabolism and embryonic development, we assessed the metabolic characteristics of myo-inositol, phosphatidylinositol 4,5-bi...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Wang X,Yue H,Li S,Guo J,Guan Z,Qin J,Zhu Z,Niu B,Cui M,Wang J

更新日期：2020-02-17 00:00:00

abstract：:BACKGROUND The aim of this study was to investigate the association between cystatin C and cardiac function and long-term prognosis in patients with chronic heart failure (CHF). MATERIAL AND METHODS We selected 418 CHF patients admitted to our hospital as subjects. Patients were divided into 3 groups according to the ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Wu X,Xu G,Zhang S

更新日期：2020-02-16 00:00:00

abstract：:BACKGROUND The hepatotoxicity of Tripterygium wilfordii Hook. f. (TWHF) limits its clinic utilization. Qingluo Tongbi formula (QTF) was formulated based on a basic Chinese medicine theory. Previous studies have confirmed the safety and efficacy of QTF in treating rheumatoid arthritis. Therefore, we considered that TWH...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Li M,Wang J,Fu L,Lu Y,Xu J,Zhou L,Zhu H,Fang L,Feng Z,Xie T,Zhou X

更新日期：2020-02-15 00:00:00